Shh Signaling Is Essential for Normal Patterning of the Digits

question 14

Multiple Choice

Shh signaling is essential for normal patterning of the digits.Fate labeling studies have shown that the digits are patterned by a combination of the dose,diffusion,and length of exposure to Shh signaling.Which digit is dependent solely on diffusion of Shh for its development?

• A) Digit 1, the most anterior (cranial) digit
• B) Digit 2
• C) Digit 3
• D) Digit 4
• E) Digit 5, the most posterior (caudal) digit

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