Nevoid Basal Cell Carcinoma or Gorlin Syndrome Predisposes Individuals to Basal

question 13

Multiple Choice

Nevoid basal cell carcinoma or Gorlin syndrome predisposes individuals to basal cell carcinomas and is due to increased activity in a signaling pathway.Which signaling pathway is activated and which component of the pathway is usually mutated?

• A) WNT, BETA-CATENIN
• B) NOTCH, HES1
• C) SHH, PTC1
• D) BMP, NOGGIN

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