Researchers Have Shown That the HoxA and D Complex of Transcription

question 8

Multiple Choice

Researchers have shown that the HoxA and D complex of transcription factors,which are expressed in nested domains within the limb bud,are essential for outgrowth and normal patterning of the limb bud.This is clearly shown by the genetic inactivation of Hoxa11 and Hoxd11.In the forelimb,which structure(s) is/are affected?

• A) Humerus
• B) Radius and ulna
• C) Carpals
• D) Metacarpals
• E) Phalanges

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