The T Cell Receptor (TCR)complex Differs from an Immunoglobulin Molecule

question 17

Multiple Choice

The T cell receptor (TCR) complex differs from an immunoglobulin molecule in which one of the following ways?

• A)On average,a TCR binds antigen with much lower affinity than does an Ig molecule.
• B)The TCR can serve as a lymphocyte antigen receptor,but an Ig molecule cannot.
• C)Only the TCR can bind soluble antigen directly.
• D)The TCRs expressed by one clone of T cells can undergo changes in constant region structure after cellular activation,whereas Ig molecules expressed by one clone of B cells do not.
• E)The TCR polypeptide chains have short cytoplasmic tails and rely on associated proteins for signaling functions,whereas membrane Ig receptors are competent signaling molecules on their own.

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