Which One of the Following Statements About the Molecules B7-1 $\gamma$

question 5

Multiple Choice

Which one of the following statements about the molecules B7-1 and B7-2 is NOT true?

• A)B7-1 and B7-2 expression on antigen-presenting cells (APCs)is upregulated by the presence of "danger" signals,such as lipopolysaccharide,as well as cytokines,such as interferon (IFN)-\(\gamma\)
• B)B7-1 and B7-2 are expressed at low levels on some resting APCs.
• C)Induction of B7-1 usually occurs before the induction of B7-2 in an immune response.
• D)B7-1 and B7-2 bind to CD28 on T cells and provide "second signals" for naive T cell activation.
• E)Activated helper T cells can induce expression of B7-1 and B7-2 on APCs via CD40L binding to CD40.

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