In Patients with Hyper IgM Syndrome,there Is a Genetically Based

question 7

Multiple Choice

In patients with hyper IgM syndrome,there is a genetically based deficiency in expression of CD40 ligand.In addition to defects in antibody isotype switching,these patients have defects in T cell-mediated immune responses and become infected with intracellular parasites.Which one of the following normal functions of CD40 ligand is important in T cell-mediated immunity?

• A)CD40-dependent isotype switching is required to produce antibody isotypes that activate T cells.
• B)CD40 ligand is required for CTL killing of CD40-expressing infected cells.
• C)CD40 ligand is required for maturation of CD4⁺ T cells in the thymus.
• D)CD40 ligand on activated T cells binds to CD40 on antigen-presenting cells (APCs),and this enhances the expression of B7-1,B7-2,and cytokines by the APCs.
• E)CD40 ligand on T cells binds to B7-1 and B7-2 on APCs,and this enhances the function of the APCs.

Differentiate between various propositions used to explain attuning to dynamic flow.

Grasp Smith's Unitary Theory of Caring, including manifesting intentions and its applications.

Explore sensory and extrasensory abilities as tools for caring in nursing practice.

Examine the concept of pandimensionality and its relevance to caring.

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Definitions:

Skilled Motor Movements

Complex movements that require precision and coordination, often learned through practice, involving the brain, nervous system, and muscular system.

Substantia Nigra

A part of the brain involved in movement control and reward, notable for its role in Parkinson's disease due to loss of dopamine-producing neurons.

Huntington Disease

A hereditary and degenerative brain disorder that affects muscle coordination and leads to cognitive decline and psychiatric issues.

Parkinson Disease

A neurodegenerative disorder affecting movement and fine muscle control, characterized by tremors, stiffness, and slowing of movement due to dopamine deficiency.