Which of the Following Statements About Ig Isotype Switching Is

question 3

Multiple Choice

Which of the following statements about Ig isotype switching is NOT true?

• A)Interleukin-4 promotes switching to the IgE isotype by increasing germline transcription of the C? exon.
• B)Isotype switching involves recombination of a V(D)J complex with downstream C region genes and the deletion of intervening DNA including other C region genes.
• C)Activation-induced deaminase (AID)is required for switch recombination.
• D)The enzymes that mediate isotype switching recognize conserved heptamer and nonamer DNA sequences adjacent to the constant region exons.
• E)The same recombined V(D)J gene complex is used to encode the antigen-binding region of the antibodies produced by a B cell before and after isotype switching.

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Definitions:

Direct Materials

Raw materials that are directly traceable and allocable to the production of specific goods or services.

Raw Materials Price Variance

The difference between the actual cost of raw materials and the standard cost multiplied by the actual quantity used.

Raw Materials Quantity Variance

The difference between the actual quantity of raw materials used in production and the estimated quantity, which can indicate inefficiencies or savings in material usage.

Materials Quantity Variance

The variance between the real amount of materials consumed in the manufacturing process and the anticipated amount, with this difference being multiplied by the per unit standard cost.