Which One of the Following Statements Regarding Positive and Negative

question 8

Multiple Choice

Which one of the following statements regarding positive and negative selection of T cells is NOT true?

• A)Thymic epithelial cells present self-peptide-MHC to developing T cells undergoing the selection process.
• B)T cells that do not recognize self-peptide-MHC die by neglect.
• C)T cells that bind too strongly to self-peptide-MHC die by Fas ligand-mediated apoptosis.
• D)During positive selection,developing T cells express higher levels of anti-apoptotic proteins such as bcl-2.
• E)A breakdown in negative selection may result in the development of some autoimmune diseases.

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