HLA Matching Between the Donor and Recipient Is Important for Progenitor

question 8

Multiple Choice

HLA matching between the donor and recipient is important for progenitor cell transplantation to avoid:

• A) graft versus host disease (GVHD).
• B) graft rejection.
• C) transfusion reactions.
• D) A and B.

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Definitions:

Purine

A nitrogen-containing compound that is one of the two types of bases found in DNA and RNA, the other being pyrimidine.

Pyrimidine

A nitrogenous base found in nucleic acids, characterized by a single ring structure, such as cytosine, thymine (in DNA), and uracil (in RNA).

Diploid

Having two of each type of chromosome characteristic of the species (2n).

Chromosomes

Structures consisting of DNA and proteins, found in the nucleus of cells, carrying genetic information in the form of genes.