Which WHO Classification for MDS Is Best Supported When the Peripheral

question 9

Multiple Choice

Which WHO classification for MDS is best supported when the peripheral blood shows a general cytopenia, 5-19% blasts with Auer rods, and less than 1 x10⁹ /L monocytes?

• A)Refractory anemia (RA)
• B)Refractory anemia with excess blasts 2
• C)5Q-syndrome
• D)Refractory cytopenia with multilineage dysplasia

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Definitions:

Enhancer

A segment of DNA that can increase the rate of transcription of genes, often located far from the gene it regulates.

Leucine Zipper Proteins

A type of protein that plays a role in regulating gene expression by forming a zipper-like structure that facilitates DNA binding.

Lnc RNAs

Long non-coding RNAs, a type of RNA longer than 200 nucleotides, that play a role in regulating gene expression but do not code for proteins.

Lnc RNAs

Long non-coding RNAs, a type of RNA which does not code for protein but plays various roles in regulating gene expression at the chromatin level.