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Large Cells with Abundant, Intensely Basophilic Cytoplasm with Prominent Cytoplasmic

question 30

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Large cells with abundant, intensely basophilic cytoplasm with prominent cytoplasmic vacuolization are identified on a peripheral smear. Multiple basophilic nucleoli are present. A starry sky appearance is seen with fields of basophilic leukemic blasts with benign macrophages that have ingested tumor cells. What leukemia should be suspected with this morphology?


Definitions:

Accumulate

The process of collecting or gathering an increasing quantity of a particular item or data points over time.

Post-Retirement Benefits

Benefits that an employee begins to receive after retiring from a company, including pensions, health insurance, and life insurance.

Contingency

A future event or circumstance that is possible but cannot be predicted with certainty.

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