A Diagnosis of CLL Requires Morphologic and Phenotypic Findings of Which

question 2

Multiple Choice

A diagnosis of CLL requires morphologic and phenotypic findings of which of the following?

• A) Variable absolute lymphocyte counts with few prolymphocytes and CD38+
• B) Sustained absolute lymphocyte counts with mature lymphocytes, few prolymphocytes, smudge cells, CD20+, and ZAP-70+
• C) Marked absolute lymphocytosis, anemia, and thrombocytopenia; prolymphocytes less than 10%
• D) Sustained absolute lymphocyte counts; mature lymphocytes; CD3−, CD2+, CD4−, CD8−, CD7+, CD16+, CD56+/CD57−

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Definitions:

Amyloidosis

A disease characterized by the accumulation of amyloid proteins in various tissues of the body, potentially leading to organ dysfunction.

Leukemia

A type of cancer that affects the blood and bone marrow, characterized by the overproduction of abnormal white blood cells.

Antigens

Foreign substances that induce an immune response in the body, especially the production of antibodies.

Antibodies

Proteins produced by the immune system to identify and neutralize foreign objects like bacteria and viruses.