CD34 Enumeration Is Useful in Bone Marrow and Peripheral Blood

question 3

Multiple Choice

CD34 enumeration is useful in bone marrow and peripheral blood stem cell transplantation.The EWGCCA recommendations for this enumeration include proper technique and interpretation of the flow cytometry analysis.Which of the following standards were recommended for proper acquisition of events?

• A)Include platelets and unlysed red blood cells and debris
• B)Include only CD34 dim staining populations
• C)Use bright fluorochrome conjugates of class II or III monoclonal antibodies that detect all glycoforms of CD34
• D)Acquire only 10 CD34 positive cells

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Definitions:

Regression Coefficient

A value that represents the degree of change of a dependent variable expected from a one-unit change in an independent variable, all else being equal.

Simple Linear Regression

A statistical technique that fits a linear equation to observed data to model the connection between a dependent variable and a single independent variable.

t-test Statistic

A test statistic used to determine if there is a significant difference between the means of two groups.

F-test Statistic

A value derived from an F-test which is used to compare statistical models in terms of variance explained by the models, to determine if the models are significantly different from each other.