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T4 and Other Bacteriophages Commonly Use a Method of DNA

question 62

Essay

T4 and other bacteriophages commonly use a method of DNA replication and packaging called ʺheadful packaging.ʺ Explain how viral genomes are replicated and packaged in this process and hypothesize how headful packaging might affect evolution of BOTH the bacteriophages and their prokaryotic hosts.


Definitions:

Hydrogen Bonds

Weak bonds between molecules or within molecules that result from an electrostatic attraction between a hydrogen atom, which is covalently bonded to a more electronegative atom, and another electronegative atom.

DNA Polymerase

An enzyme that synthesizes DNA molecules from deoxyribonucleotides, the building blocks of DNA.

Watson-Crick Model

A structural model of DNA proposed by James Watson and Francis Crick, illustrating DNA as a double helix composed of two antiparallel strands.

Sugar-Phosphate

Refers to the backbone of DNA and RNA, composed of alternating sugar and phosphate groups that hold together the nucleotide bases.

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