If You Mutate the Cyclin-Binding Site on a Cdk Such

question 34

Multiple Choice

If you mutate the cyclin-binding site on a Cdk such that Cdk cannot bind to cyclin,what effect would you expect to see?

• A)Cdk will be unaffected.
• B)The cell cycle will be up-regulated,and cells will proliferate.
• C)Cdk will be inactive,so the target proteins will not be phosphorylated.
• D)Cdk will be constitutively active,so the cell cycle will be unchecked.
• E)Cdk will phosphorylate its target proteins regardless of the cell cycle.

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Definitions:

Cerebrospinal Fluid

The clear, colorless body fluid found in the brain and spinal cord, providing cushioning and nutrients.

Spinal Cord

The nervous tissue within the spinal column that transmits nerve signals between the brain and the rest of the body.

Conus Medullaris

The tapered, lower end of the spinal cord, occurring around the lumbar vertebral levels 1 (L1) to 2 (L2).

Lumbar Enlargement

A widened area of the spinal cord that gives rise to nerves which innervate the lower limbs.