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What Type of Mutation Commonly Affects CpG Islands, Altering Promoter

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What type of mutation commonly affects CpG islands, altering promoter regions of mammalian genes?

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Definitions:

Brake Dust

The accumulation of particulate matter produced from the friction material of brake pads rubbing against the brake disc when the brakes are applied, often seen on the wheels of cars.

Hydraulic System

A system that uses fluid under pressure to power machinery or move mechanical components.

Brake Pedal

A mechanism that activates the brake system in a vehicle, allowing the driver to slow down or stop the vehicle by pressing down with their foot.

Drum Facing

The process of machining the surface of a brake drum to ensure it is smooth and even for better brake performance.

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