Now That Small Molecular-Level Deletions and Subtle Chromosomal Rearrangements Can

question 30

Essay

Now that small molecular-level deletions and subtle chromosomal rearrangements can be discovered using advanced cytogenetic techniques and microarrays,disorders whose causes had not previously been known can have their basis identified.However,since most of these are not widely publicized,being individually rare,it has been difficult to identify patients with shared chromosomal abnormalities who share phenotypic features.A new database,known as DECIPHER,is now available to search for patients with like phenotypes and/or like chromosomal abnormalities.If you are the clinical geneticist who has a patient whose data is entered into this database,suggest three or more ways in which this could be useful either to you or to the patient.

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Definitions:

Debit

To deduct, to charge; a charge added to existing balance.

Personal Identification Number

A unique numerical code used in securing access to accounts or systems, often a password or security measure.

Payee's Signature

The signature of the individual or entity entitled to receive payment on a financial document, such as a check.

Back Of A Check

The rear face of a check where endorsements are made, including the signature of the recipient, necessary for the check to be cashed or deposited.