You Are a Genetic Counselor Working with a Phenotypically Normal

question 42

Multiple Choice

You are a genetic counselor working with a phenotypically normal young couple who have been referred because the wife has a family history of a mitochondrial disorder that results in considerable dysfunction. What is the most important consideration you can suggest?

• A)to refrain from having children that are hers biologically
• B)that she be tested to find out what percentage of her mitochondria bear the mutation
• C)that both husband and wife have mtDNA testing for the sequence in question
• D)that her affected mother's DNA be tested
• E)that they consider having only sons

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Definitions:

Cost of Capital

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Risk Level

The degree of uncertainty and the potential financial loss associated with an investment or business decision.

Net Present Value

An evaluation metric that analyzes the profitability of a projected investment by discounting future cash flows to their present value and subtracting the initial investment cost.

Project Rate of Return

The expected return on an investment, estimating the profitability of a project or investment.