Alterations in the Ratio of CD4:CD8 Lymphocytes Are Associated with Risk

question 20

Multiple Choice

Alterations in the ratio of CD4:CD8 lymphocytes are associated with risk of HIV infection progressing to AIDS,of autoimmune diseases,and of progression of some cancers.In searching for predictors of these effects in normal individuals,researchers have found two independent QTLs in the region of the genome known as the major histocompatibility complex (MHC) ,one in a region regulating CD8 and the other in a region regulating CD4.What does this indicate for the general population?

• A)Mutation in one or both of these genes causes HIV and AIDS.
• B)Autoimmune diseases such as type 1 diabetes are caused by one of these genes.
• C)Variation in one or the other of these genes may increase the risk of autoimmune diseases.
• D)Only one mutation can be the cause of rheumatoid arthritis.
• E)The probability of an autoimmune disease demonstrates that additive genes are involved.

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Definitions:

Erotophilic

Referring to an attitude toward sexual activity that is positive, embracing sexual pleasure and diversity of sexual expressions.

Sexual Fantasies

Imaginative thoughts or mental images about sexual activity that can intensify sexual desire and arousal.

Sexual Scripts

Socially learned guidelines that dictate how individuals should behave in sexual contexts, including roles, actions, and expectations.

Sexual Behavior

Actions or practices related to the expression of sexuality, including sexual activity and choices regarding sexual partners.