Mean Platelet Volume (MPV)in Humans Increases with Heart Attacks and Strokes

question 24

Multiple Choice

Mean platelet volume (MPV) in humans increases with heart attacks and strokes and is used to predict recurrence as well as mortality.MPV has high heritability.A recent GWA study found MPV to be associated with three SNPs on chromosomes 12,3,and 17 respectively.These three QTLs accounted for 4-5% of MPV variance.Which of the following is a reasonable explanation?

• A)Other loci may also account for significant variance of MPV.
• B)These SNPs must be translocated or transposed alleles.
• C)Monitoring of these SNPs should identify those at highest risk.
• D)The three SNPs,when sequenced,should show high conservation.
• E)The three SNPs will be found in genes responsible for stroke.

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Definitions:

Normal Time

The average time taken by a worker to complete a task under normal working conditions.

Standard Time

The established duration designed for the completion of a specific task, under normal working conditions and performance.

Time Study

A work measurement technique for recording the times of performing a task to establish a standard time for the activity by direct observation and timing.

Labour Standard

Labour standard represents the amount of time required to perform a job or part of a job at a defined level of performance, often used in planning and evaluating labor efficiency.