The Problem Below Relates to the Synthesis of Several Intermediates

question 9

Short Answer

The problem below relates to the synthesis of several intermediates in the citric acid cycle,which is essential in the production of ATP through aerobic respiration.A set of experimental results relating the growth (+)of Neurospora on several media is given in the table.Based on the information provided,present the biochemical pathway for the substances oxaloacetate,fumarate,malate,and succinate,and the locations of the metabolic blocks produced by the various strains.
$$\begin{array} {c}\underline {\text { Medium }}\quad\quad\quad\\\begin{array} { l c c c c c } \text { Strain } & \text { MM } & \begin{array} { c } \text { MM } \\\text { + oxaloacetate }\end{array} & \begin{array} { c } \text { MM} \\\text {+ fumarate }\end{array} & \begin{array} { c } \text { MM } \\+ \text { malate }\end{array} & \begin{array} { c } \text { MM } \\+ \text { succinate }\end{array} \\\hline 162 & - & + & - & + & - \\136 & - & + & - & - & - \\141 & - & + & + & + & -\end{array}\end{array}$$

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Definitions:

Disturbance of Attention

A reduction in the ability to focus the mind on a single task or object, often associated with conditions like ADHD.

Word Salad

A disorganized speech pattern characterized by a random, incoherent mix of words, phrases, or concepts.

Delusions

False beliefs held with strong conviction despite superior evidence to the contrary, often encountered in psychiatric disorders like schizophrenia.

Hallucinations

Perceptions in the absence of external stimuli that are experienced with a vivid sense of reality.