What Is One Major Limitation of Two-Dimensional Gel Electrophoresis (2-DGE)

question 28

Multiple Choice

What is one major limitation of two-dimensional gel electrophoresis (2-DGE) ?

• A) It is extremely costly to execute in a typical molecular biology laboratory.
• B) When products are separated, they tend to leach out of the gel matrix.
• C) Only the most abundant products are detected.
• D) 2-DGE can be run only on nucleic acids.
• E) 2-DGE is useful only in separating eukaryotic gene products.