What Is an Allele-Specific Oligonucleotide

question 17

Essay

What is an allele-specific oligonucleotide?

---

Definitions:

RAS

Acronym for the Reticular Activating System, a network of neurons located in the brainstem that regulates wakefulness and sleep-wake transitions.

Sleep-Wake Cycle

The circadian rhythm that regulates periods of sleepiness and wakefulness throughout a 24-hour period.

Narcolepsy

A rare condition with symptoms that can include sleep paralysis and cataplexy.

Insomnia

A sleep disorder characterized by trouble falling asleep, staying asleep, or experiencing restorative sleep, leading to daytime dysfunction.