Which of the Following Is NOT True of Familial Aggregation

question 2

Multiple Choice

Which of the following is NOT true of familial aggregation of a trait?

• A) One should compare the clustering of the trait in affected families compared to the general population
• B) Family clustering proves there is a genetic contribution to the trait
• C) Increased trait sharing in monozygotic compared to dizygotic twins suggests a genetic contribution to the trait
• D) Traits with a genetic liability will show familial aggregation
• E) These studies can be plagued by ascertainment bias

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