Which of the Following Is True of CFTR Mutations

question 6

Multiple Choice

Which of the following is true of CFTR mutations?

• A) Mutations affecting the function of CFTR are always associated with a classic CF phenotype
• B) There are clear genotype-phenotype correlations for CFTR mutations
• C) Mutations can present as congenital bilateral absence of the vas deferens as the sole phenotype
• D) The IVS8 9T variant allele causes classic CF
• E) Pancreatic insufficiency is rarely found in people with the DF508 mutation