Sickle Cell Anemia (A Serious Heritable Disease)appears to Be Maintained

question 24

Multiple Choice

Sickle cell anemia (a serious heritable disease) appears to be maintained via balancing selection in some African populations because heterozygous carriers for the fully recessive disease allele are less affected by malaria parasites.Is this a case of antagonistic pleiotropy?

• A)Yes, the same allele has positive effects on one trait and negative effects on another trait.
• B)Yes, wild-type and sickle cell alleles have antagonistic effects.
• C)No, there is no time lag between the two traits (i.e., as in early vs. late acting).
• D)No, it involves a dominance interaction between the wild-type and the sickle cell allele.

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