The Relationship Between Brain-Derived Neurotrophic Factor (BDNF)and Bipolar Disorder Can

question 149

Multiple Choice

The relationship between brain-derived neurotrophic factor (BDNF) and bipolar disorder can best be described as:

• A)strong - BDNF gene variation predicts bipolar disorder
• B)inconsistent - BDNF gene variation predicts bipolar in some but not all ethnicities
• C)nonexistent - BDNF gene variation has been linked to depression but not bipolar
• D)weak - BDNF gene variation only sometime predicts one type of bipolar disorder (i.e., rapid cycling)

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Definitions:

Substance P

A neuropeptide involved in pain perception and the inflammatory response within the body.

Endorphin

Natural peptides produced by the brain that act as neurotransmitters to reduce pain perception and lead to feelings of euphoria.

Serotonin

A neurotransmitter that contributes to feelings of well-being and happiness, also involved in the regulation of mood, sleep, and appetite.

Substance P

A neuropeptide involved in the transmission of pain and other sensory signals to the brain, also implicated in inflammatory processes.