In the Condition Diabetes Mellitus,why Does Glucose Appear in the Urine

question 16

Multiple Choice

In the condition diabetes mellitus,why does glucose appear in the urine? 

• A)The plasma concentration of glucose becomes so high that it diffuses from peritubular capillaries into the proximal tubule,down its concentration gradient.
• B)The filtered load of glucose becomes greater than the tubular maximum for its reabsorption.
• C)Without the hormone insulin,glucose cannot enter proximal tubule epithelial cells.
• D)The rate of tubular secretion of glucose becomes greater than the sum of glucose filtration and reabsorption.
• E)Without insulin,the glomerular filtration barrier becomes extremely leaky to glucose,which is not normally filterable.

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