Why Is It Important for T Cells to Weakly Recognize

question 7

Essay

Why is it important for T cells to weakly recognize self MHC proteins while strong recognition is problematic?

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Definitions:

Founder Effect

After a small group of individuals found a new population, allele frequencies in the new population differ from those in the original population.

Limited Gene Pool

Refers to a small variety of genes in a population, which can lead to decreased genetic diversity and increased susceptibility to diseases or genetic abnormalities.

DNA Sequence

The precise order of nucleotides within a DNA molecule, which determines genetic information.