A Patient Has Been Diagnosed with Acute Lymphocytic Leukemia (ALL)

question 10

Multiple Choice

A patient has been diagnosed with acute lymphocytic leukemia (ALL) and asks the healthcare professional to describe it. What description by the professional is most accurate?

• A)ALL is a progressive neoplasm defined by the presence of greater than 30% lymphoblasts in the bone marrow or blood.
• B)In ALL, immature blasts cells replace normal myelocytic cells, megakaryocytes, and erythrocytes.
• C)B cells fail to mature into plasma cells that synthesize immunoglobulins.
• D)The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL.

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Definitions:

Hemichannel

A type of membrane channel that allows the exchange of ions and small molecules between the intracellular space and the extracellular environment.

Gap Junction

Area of contact between adjacent cells in which connexin proteins in each cell form connecting hemichannels, which, when open, allow ions to pass between the two cells; also called an electrical synapse.

Interneuronal Communication

The transfer of information between neurons within the nervous system, facilitating brain and body functions.

Gap Junctions

Specialized intercellular connections that facilitate direct electrical and chemical communication between cells.