Reoviruses Keep Their Genome Sequestered Inside the Inner Capsid Throughout

question 21

Multiple Choice

Reoviruses keep their genome sequestered inside the inner capsid throughout the entire infectious cycle.Which of the following is the best explanation for why do they not release the genome segments out into the cytoplasm?

• A) The double-stranded RNA segments activate the interferon response.
• B) There are cellular enzymes that specifically degrade double-stranded RNA.
• C) The RNA segments can not be translated by the cellular ribosomes.
• D) Double-stranded RNA is sequestered into special compartments within the cytoplasm.
• E) There are cellular proteins that will bind double-stranded RNA and inhibit it.

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