Binding of the Large T Antigen of SV40 to the Cellular

question 8

Multiple Choice

Binding of the large T antigen of SV40 to the cellular protein pRb causes which of the following to occur?

• A) Degradation of the cellular protein p53
• B) Activation of the apoptosis pathway.
• C) Replication of viral DNA
• D) Dissociation of the transcription factor E2F.
• E) Blocks progression through the cell cycle.

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Definitions:

Cerebellum

A region of the brain that plays an important role in motor control, coordination, precision, and timing of movements.

Basal Ganglia

A group of nuclei in the brain involved in coordinating movement, as well as aspects of learning and emotion.

Flexor Muscles

Muscles that decrease the angle between bones on two sides of a joint, involved in bending or flexing parts of the body.