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Monkeys infected with a mutant of SIV that lacks the Nef coding sequence have reduced virus titers and less severe disease.
Membrane-bound Receptor Model
A conceptual model describing receptors located on the cell membrane that interact with external signals (ligands) to initiate cellular responses.
Membrane-bound Receptor
A type of receptor that is attached to the cell membrane and is involved in signaling pathways following the binding of a ligand.
Cyclic AMP
A second messenger molecule important in many biological processes, such as signal transduction and intracellular communication.
Adenylyl Cyclase
An enzyme that converts ATP to cyclic AMP, playing a critical role in cell signaling pathways.