Which of the Following Observations About the PrPˢᶜ Protein Could

question 20

Multiple Choice

Which of the following observations about the PrPˢᶜ protein could explain how this protein causes damage to the neurons of the brain?

• A) The PrPˢᶜ protein causes glycosylation of membrane proteins to become disregulated.
• B) The PrPˢᶜ protein causes copper to be sequestered in neurons.
• C) The PrPˢᶜ protein is more resistant to protease digestion than the cellular form.
• D) The PrPˢᶜ protein alters the signaling pathways in neurons.
• E) The PrPˢᶜ protein aggregates to form fibrils.

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Definitions:

Duplication

The act of making an exact copy of something; in genetics, it refers to a type of mutation where segments of DNA are repeated.

Postal Money Order

A financial instrument, purchased from a postal authority, used to pay a specified amount of money to someone else.

Endorsement

The act of giving one's public approval or support to someone or something, or in financial terms, the signature on the back of a check that allows it to be deposited or cashed.

Subtle Gradations

Fine or slight differences or variations within a range or series of elements or aspects.