How Does the Capsid-Binding Drug Pleconaril Inhibit Entry of Picornavirus

question 20

Multiple Choice

How does the capsid-binding drug pleconaril inhibit entry of picornavirus particles?

• A) It causes antibodies to bind to the capsid and blocks entry.
• B) It causes the capsid to become degraded by proteases.
• C) It binds to the same location on the capsid as the host cell receptor.
• D) It displaces a lipid normally bound to a pocket on the capsid.
• E) It binds to the envelope of the virus and prevents it from fusing with the plasma membrane.

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