Staphylococcal Exfoliative Toxin (Exfoliatin A) Reacts in the Human Body

question 34

Multiple Choice

Staphylococcal exfoliative toxin (exfoliatin A) reacts in the human body as a superantigen. Intoxication with this means:

• A) polyclonal T-cell stimulation by overriding the normal route of antigen presentation
• B) monoclonal B-cell stimulation without T-cell signaling
• C) direct overactivation of T_H1 cells, causing a T_C cell response only
• D) dramatic down-regulation in genes that control all cells producing pro-inflammatory cytokines
• E) decreased antigen presentation by the antigen-presenting cells, followed by autoantibody formation

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