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One Group of 20 Patients Is Given a Drug That

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One group of 20 patients is given a drug that is thought to have an effect on kidney function, and another group of 20 patients is given a placebo (i.e., sugar pill, which is known not to have an effect on kidney function) .The nuclear medicine gamma camera is used to calculate the glomerular filtration rate (GFR) in these two groups of patients.What would be the proper statistical test to use to test the hypothesis that no difference in GFR exists between these two groups of patients?


Definitions:

Confounding Variable

An outside influence that changes the effect of a dependent and independent variable being examined in an experimental or observational study.

Independent Variable

A variable in an experiment that is manipulated or changed by the researcher to observe its effects on the dependent variable.

Covaries

When two variables change in relation to each other, suggesting a potential relationship or correlation between the two.

Double-Blind Procedure

A research or testing method in which neither the participants nor the experimenters know who is receiving a particular treatment, to prevent bias.

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