SCID Is Defined by a Lack of Functional B and T

question 62

Multiple Choice

SCID is defined by a lack of functional B and T cells which eliminates protection by humoral and cell-mediated immunity.Which of the following is true?

• A)A genetic defect disrupts the development of the lymphocytic cell lines.
• B)A genetic mutation renders the individual incapable of removing a toxic DNA metabolite from lymphocytes, which ultimately destroys them.
• C)Genes coding for B and T cell receptors are mutated so the cells are incapable of binding antigens.
• D)Genes that code for interleukin receptors are mutated so the individual's B and T cells do not receive the activation signals, rendering them useless.
• E)All of the above describe cases of SCID.

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