Mutations That Affect the Binding of an SR Protein to an Exonic

question 44

Multiple Choice

Mutations that affect the binding of an SR protein to an exonic splicing enhancer can cause exon skipping in some genes,producing mRNAs that when translated yield nonfunctional proteins.In addition to an RNA-binding domain,SR proteins also contain an RS domain that is involved in binding:

• A)DNA.
• B)RNA.
• C)protein.
• D)none of the above

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Definitions:

Sound Waves

Waves of sound that propagate through air or other materials, perceived when they make contact with an individual's or an animal's ear.

Amplitude

In physics, it is the maximum extent of a vibration or oscillation, measured from the position of equilibrium.

Pitch

A term that can refer to the perceived frequency of a sound, often described as how "high" or "low" a note sounds.

Nerve Hearing Impairment

A type of hearing loss resulting from damage or dysfunction of the auditory nerve, affecting the transmission of sound signals to the brain.