Which of the Following Statements Best Describes the Difference Between

question 11

Multiple Choice

Which of the following statements best describes the difference between low-affinity integrins and high-affinity integrins?

• A)Many integrins can exist in two conformations: a low-affinity (bent)conformation and a high-affinity (straight)conformation.
• B)Dissociation of the αβ heterodimer converts many integrins from the low-affinity to the high-affinity state.
• C)Association of the αβ heterodimer converts many integrins from the low-affinity to the high-affinity state.
• D)Proteolytic cleavage of the C-terminal tails of the two subunits converts many integrins from the low-affinity to the high-affinity state.