In Cells with Mutations in Either TAP1 or TAP2

question 15

Multiple Choice

In cells with mutations in either TAP1 or TAP2:

• A)ubiquitin conjugation would be disrupted and antigen proteins would not be tagged for destruction.
• B)ubiquitin-conjugated proteins would not be destroyed by proteasomal proteolysis.
• C)peptides generated by proteasomal proteolysis would not be complexed with class I MHC molecules.
• D)class I MHC-antigen complexes would be unable to cross the ER membrane.

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Term used in the 1920s, in reference to a slow and steady growth of black political influence that occurred in northern cities, where African-Americans were freer to speak and act. This political activity created a spirit of protest that expressed itself culturally in the Harlem Renaissance and politically in “new Negro” nationalism.

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