A Bone Tumor Sample Appears to Be Heterozygous for a P53

question 23

Multiple Choice

A bone tumor sample appears to be heterozygous for a p53 mutation.The most likely explanation for this finding is:

• A)Mutated p53 is an oncogene.
• B)The p53 mutation is resulting in a dominant negative p53 protein.
• C)The p53 mutation is resulting in a premature stop codon,and no functional protein is made from that allele.
• D)There was a mistake in labeling the tissue sample-all tumors musts lack p53.

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