How Does Tissue Damage Occur in Acute Rejection After an Organ

question 39

Multiple Choice

How does tissue damage occur in acute rejection after an organ transplant?

• A) Helper T cells (Th1)release cytokines that activate infiltrating macrophages and cytotoxic T cells directly attack the endothelial cells of the transplanted tissue.
• B) Circulating immune complexes are deposited in the endothelial cells of transplanted tissue where the complement cascade lyses tissue.
• C) Antigens on the cell surface of transplanted tissue are recognized by receptors on natural killer (NK)cells,which release lysosomal enzymes that destroy tissue.
• D) Antibodies coat the surface of transplanted tissue to which mast cells bind and liberate preformed chemical mediators that destroy tissue.

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