How Is Sickle Cell Trait Different from Sickle Cell Disease

question 16

Multiple Choice

How is sickle cell trait different from sickle cell disease?

• A) The child with sickle cell trait inherited normal hemoglobin A from one parent and hemoglobin S (Hb S)from the other parent,whereas the child with sickle cell disease has HbS from both parents.
• B) The child with sickle cell trait has a mild form of sickle cell disease that causes sickling during fever and infection,but not during acidosis or hypoxia,whereas the child with sickle cells disease develops sickling during each of these conditions.
• C) The child with sickle cell trait has a milder form of the disease that is characterized by vaso-occlusive crises and believed to result from higher hemoglobin values and viscosity.
• D) The child with sickle cell trait has the mildest form of the disease with normal hemoglobin and hemoglobin F,which prevents sickling.

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