Erythropoietin (EPO)was First Isolated from the Urine of Anemic Patients

question 41

Essay

Erythropoietin (EPO)was first isolated from the urine of anemic patients who had high circulating levels of the hormone.Despite the presence of the hormone that stimulates red cell production, however, these patients were unable to produce adequate amounts of hemoglobin or red cells.Give some possible reasons that the patients' own EPO was unable to correct their anemia.

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