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Randomized controlled trials cannot:
Mediastinum
The central compartment of the thoracic cavity surrounded by loose connective tissue, containing the heart, esophagus, trachea, major blood vessels, and other structures.
Pleural Fluid
The thin layer of fluid between the two pleurae (the membranes surrounding the lungs and lining the chest cavity) that lubricates and facilitates lung movement during breathing.
Inspiratory Muscles
Muscles involved in inhalation, primarily the diaphragm and intercostal muscles, which expand the thoracic cavity.
Pleural Pressure
The pressure within the pleural cavity, which can influence lung expansion and contraction.
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