In Individuals with Normal Blood Sugar Levels,glucose Is Reabsorbed into the Bloodstream

question 53

Multiple Choice

In individuals with normal blood sugar levels,glucose is reabsorbed into the bloodstream in the kidney by members of the GLUT transporter family,which form an aqueous pore across the membrane through which glucose can move in a passive manner.As a result,no glucose is excreted in urine.However,in people with untreated diabetes mellitus,blood sugar levels are high and glucose is often present in the urine.Which of the following best explains this occurrence?

• A)High blood glucose levels reverse the concentration gradient,allowing untransported glucose to be excreted in urine.
• B)High blood glucose levels interfere with the coupled transport of water and glucose,allowing untransported glucose to be excreted in urine.
• C)The GLUT transporters become saturated,allowing untransported glucose to be excreted in urine.
• D)The GLUT transporters cannot hydrolyze ATP quickly enough for ATP to transport the extra glucose,thereby allowing untransported glucose to be excreted in urine.

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