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The purchasing manager is evaluated by his/her supervisors based on purchasing inventory at the lowest price. Consequently, the purchasing manager knowingly orders materials only based on price. This has resulted in the purchase of inferior quality materials. This improved the purchasing manager's performance evaluation, but had a negative impact on production due to an increase in scrapped materials. This situation is an example of a failure of:
Upstream Promoter Elements
Regions of DNA located before (upstream of) the coding sequence of a gene that help initiate transcription by providing binding sites for RNA polymerase and transcription factors.
Eukaryotes
Organisms whose cells have a nucleus enclosed within a nuclear envelope, making up one of the three recognized domains of life, including plants, animals, fungi, and protists.
Transcription Initiation
The first stage of gene expression in which the enzyme RNA polymerase binds to a promoter region of DNA, starting the process of RNA synthesis.
TATA Box
A DNA sequence found in the promoter region of genes, indicating where transcription begins; crucial for gene expression.
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