In the Familial Form of Retinoblastoma,individuals Who Inherit One Mutant

question 37

Essay

In the familial form of retinoblastoma,individuals who inherit one mutant allele of the RB1 gene have an 85% chance of developing retinoblastoma and other cancers.Explain why,when these individuals carry only one copy of the mutant gene,there is such a high incidence of cancer in these RB1 heterozygotes.

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Definitions:

Negative Net Cash Flow

A situation where a company's outgoing cash exceeds the incoming cash during a specific period, indicating potential financial trouble.

Financial Statements

Structured reports that detail the financial performance of an organization, typically including the balance sheet, income statement, and cash flow statement.

Depreciation Expenses

The allocation of the cost of tangible assets over their useful lives, recognized as an expense on the income statement.

Retained Earnings

Profits that a company chooses not to distribute as dividends to shareholders but instead reinvests in the business or keeps as reserve.