Some People Are Unable to Properly Metabolize the Drug Purinethol,which

question 23

Multiple Choice

Some people are unable to properly metabolize the drug Purinethol,which is given to patients with acute lymphoblastic leukemia; therefore,such patients must be first tested for the associated genetic variant to determine proper dosage of the drug. This scenario best illustrates the use of _____.

• A) pharmacogenomics
• B) map-based sequencing
• C) positional cloning
• D) annotation of DNA sequences
• E) comparative genomics

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Definitions:

Proctoplasty

Surgical reconstruction of the rectum, often to repair damage or correct malformations.

Laparotomy

A surgical procedure involving a large incision in the abdomen to gain access to the abdominal cavity for diagnosis or treatment.

Choledochotomy

a surgical incision into the common bile duct, typically to remove gallstones.

Gastrectomy

A surgical procedure for the partial or total removal of the stomach.